Study: Full-Spectrum CBD Extract Reduced Meth Relapse-Like Behavior Better than CBD Alone
A study published by the journal Progress in Neuro-Psychopharmacology and Biological Psychiatry found that a full-spectrum CBD extract reduced relapse-like methamphetamine seeking and meth-triggered hyperactivity in an animal model better than CBD alone. Researchers from Macquarie University and University of Sydney tested whether a multi-cannabinoid hemp extract could outperform a single-cannabinoid CBD isolate in several established rat models used to study drug-seeking and relapse. For the study, male Sprague-Dawley rats were trained to self-administer methamphetamine by lever press, then underwent extinction sessions where lever presses no longer
Study Finds CBD May Support Bone Formation, Strength, and Healing Through Multiple Biological Pathways
A new review published in Biomedicines is adding to the growing body of research suggesting that cannabidiol (CBD) could play a meaningful role in bone health. Conducted by researchers from Universiti Kebangsaan Malaysia, the scoping review examined 24 original studies exploring how CBD affects bone-related outcomes across a range of experimental models. The researchers conducted a systematic search of major scientific databases and analyzed studies regardless of design, focusing on CBD’s effects on bone formation, mineralization, strength, and underlying biological mechanisms. Of the 24 studies
Cannabis Oil Combined With Physiotherapy Reduced Post-Stroke Tremor and Thalamic Pain in Case Report
A case report published in Current Neuropharmacology by researchers from the University of Catania details how a combination of cannabis oil and physiotherapy was associated with substantial improvements in a patient suffering from post-stroke dystonic tremor and post-stroke thalamic pain, two conditions that are often difficult to treat with conventional medications. Post-stroke tremor and thalamic pain are known to significantly reduce quality of life, and standard pharmacological treatments frequently provide limited relief. While cannabis has been explored for its potential role in treating movement disorders and chronic
Study: CBD Reduced Incision-Related Wound Pain in Preclinical Model, Altered Endocannabinoid Activity in Brain and Spinal Cord
New research published in the peer-reviewed journal Pharmaceuticals and conducted by researchers from the University of Galway found that cannabidiol (CBD) may reduce pain associated with surgical-type wounds.Using male Sprague-Dawley rats, researchers created a small incision on the dorsum (back) to model wound-related pain, a condition that remains common and often poorly managed in clinical settings. Mechanical pain sensitivity was measured over several days using standardized von Frey tests on both the wound site and the hind paws to assess primary and secondary hypersensitivity. By the eighth
Study Published in Canadian Journal of Pain Finds Medical Marijuana Linked to Improvements in Pain, Mental Health and Quality of Life
A study published by the Canadian Journal of Pain reports that patients with chronic pain who used medical marijuana experienced measurable improvements in pain-related outcomes, mental health indicators and overall quality of life over a 24-week period.The prospective observational study was led by Dr. Hance Clarke, Director of Pain Services at University Health Network in Toronto, and was published this week in the Canadian Journal of Pain. The research evaluated patient-reported outcomes among individuals receiving medical marijuana under the supervision of a health-care provider as part of
Study: CBD Linked to Major Seizure Reductions in Those With Severe, Drug-Resistant Epilepsy Across Genetic and Acquired Causes
A new study published in the journal Medicine by researchers from Korea University College of Medicine provides further evidence that cannabidiol (CBD) can substantially reduce seizures in children and young adults with some of the most difficult-to-treat forms of epilepsy, even when the condition stems from a wide variety of genetic, structural, and acquired causes. The retrospective cohort study examined 29 patients with pediatric-onset, intractable epilepsy treated with adjunctive CBD therapy at Korea University Hospitals over a five-year period. Patients had seizure onset at a median age
Study: Female Marijuana Plants Contain Nearly 17 Times More CBD Than Males, Researchers Identify the Exact Genes Responsible
A new peer-reviewed 0 published in iScience by researchers from the Institute of Bast Fiber Crops at the Chinese Academy of Agricultural Sciences provides one of the clearest molecular explanations yet for why female marijuana plants are dramatically more valuable for cannabinoid production than male plants. Using a combined transcriptomic and metabolomic analysis of male and female Cannabis sativa flowers, the research team identified 1,676 differentially expressed genes and 700 differentially accumulated metabolites that separate the two sexes at the biochemical level. The results show
Study: CB2 Activation May Reduce Lung Injury Caused by COVID-19
A new study published in the journal Lung by researchers at Eastern Virginia Medical School at Old Dominion University reports that activating the cannabinoid type 2 receptor (CB2) may help prevent lung damage caused by COVID-19. Using an animal model designed to mimic acute lung injury tied to the virus’s spike protein, the researchers triggered lung damage by delivering SARS-CoV-2 spike protein subunit 1 directly into the airways. One hour later, the animals were treated with HU308, a compound that activates CB2, and then received repeat doses
Study: CBD Protects Human Skin From Air Pollution Damage
A study published in the journal Biomolecules finds that cannabidiol (CBD) can help shield human skin from damage caused by air pollution.Researchers from the National Science and Technology Development Agency and Chulalongkorn University in Thailand used full-thickness human skin samples to examine how particulate matter (PM), a common air pollutant, affects skin health. PM is known to accelerate skin aging, trigger inflammation and weaken the skin’s protective barrier. In the study, skin samples were exposed to PM for 48 hours. Some samples were also treated with CBD.
Study: CBD Reduced Heart Damage, Boosted Mitochondrial Health in Animal Model of Heart Attack Injury
A study published today in the Journal of Cardiovascular Pharmacology found that CBD significantly reduced heart damage caused by ischemia-reperfusion injury, while boosting key markers tied to mitochondrial health, in an animal model. Researchers from Suleyman Demirel University and Burdur Mehmet Akif Ersoy University examined whether CBD could protect the heart after a temporary blockage of the left anterior descending coronary artery, followed by restored blood flow — a process known to trigger oxidative stress, inflammation and cell death. Forty rats were divided into four groups: sham,
TAC vs THC: Why Total Active Cannabinoids Matter
If you’ve ever looked at a cannabis product label, you likely noticed that it is VERY different from anything you’d find on food packaging. That’s because there are hundreds of different compounds present in the cannabis plant, each with its own potential experiences. However, one of the most confusing percentages found on marijuana labels is “TAC.” We get plenty of questions about this number–specifically how it relates to THC. In this guide, we’ll explain: TAC Also: Total Active Cannabinoids TAC indicates the total number
What Is TAC And Why Is It Important?
As cannabis legislation relaxes across the world, we’re finding out more about what this versatile herb has to offer. The TAC (total active cannabinoids) of a strain provides greater insight into the overall cannabinoid content of the plant, thereby making it possible for users to fine-tune their cannabis experience. With more attention being directed toward cannabinoids other than THC, it’s understandable that cannabis users would want to know the full extent of the cannabinoids present in their strains. Lucky for some, in regions with established
TAC vs THC: Understanding the Differences
Bought legal weed from a dispensary or other licensed retailer? If so, you might have run into the term TAC on its label. Often confused with THC or believed to be synonymous for “potency”, TAC (Total Active Cannabinoids) is an important unit of measure for cannabis products. Keep reading to learn why. As the laws around cannabis change, governments with new legal weed markets are moving fast to find ways to regulate cannabis products and ensure their quality. If you’re lucky enough to live in
Over 70 Cannabis-Related Studies Published in 2026 Highlight the Diverse Medical Potential of Cannabis
Below is a breakdown of more than 70 studies published in 2026 covering cannabis and compounds such as CBD, THC and CBG. The findings span pain relief, cancer, brain injury, sleep, metabolism, inflammation, wound healing and industrial hemp applications, underscoring just how broad the field has become. The title of each section below links to a full article on The Marijuana Herald. Clinical Trial: Cannabis-Based Herbal Formula Matches Lorazepam for Chronic Insomnia Relief A clinical trial found that a cannabis-based herbal formula performed similarly to
President Trump Expected to Sign Executive Order Creating Cannabis Descheduling Commission This Summer
The Marijuana Herald – Marijuana news and information President Trump is planning to sign an executive order this summer creating a federal commission to study the descheduling of marijuana, according to two sources who spoke with The Marijuana Herald. The move is expected to be made ahead of the November midterms. One of the sources is a longtime senior advisor to Trump, who said the commission would consist of around a dozen members and would be tasked with examining the potential ramifications of removing marijuana
The 10 Most Popular Cannabis Strains Across the United States (as of March, 2026)
The Marijuana Herald – Marijuana news and information Using a combination of data provided by state cannabis commissions, the strain review site Leafly, and the research firm Headset, below is a list of the most popular cannabis strains throughout the United States as of March, 2026. Blue Dream Blue Dream continues to hold its place as the most recognizable and widely embraced strain in the country. Although it hasn’t topped the most popular strain list in several months, its increased presence going into March, 2026
The Best Selling Cannabis Strain in Every Recreational State for February 2026
In February 2026, legal marijuana markets across the country saw familiar heavyweights maintain their grip on the top spot, even as a handful of fast-rising contenders continued to narrow the gap in several states. February sales data indicates that while many January leaders remained unchanged, shifting buying trends and regional demand pushed certain strains higher in competitive markets, underscoring how quickly consumer preferences can evolve month to month. Drawing from monthly sales reports released by state regulatory agencies and marijuana commissions—along with supplemental data from
Q&A: Cannabis usage in middle-aged, older adults linked to larger brain volume, better cognitive function
Research studying the effects of cannabis on the brain has often focused on adolescents, but a new study from CU Anschutz researchers looks at population-level impacts of cannabis usage on the brain in older adults. The work is published in the Journal of Studies on Alcohol and Drugs. “More older adults are using cannabis. It’s more widely available and is being used for different reasons than in younger folks—such as for sleep and chronic pain,” said Anika Guha, Ph.D., a clinical psychologist and faculty research associate in the
Study: Lifetime Cannabis Use Linked to Greater Cognitive Performance in Aging Populations
Aging adults with a history of cannabis use exhibit greater cognitive performance than those with no or little history of past use, according to data published in the Journal of Studies on Alcohol and Drugs. A team of researchers affiliated with the University of Colorado and Georgia Tech assessed cognitive performance and brain volume in a nationally representative sample of more than 500,000 adults (ages 40-70) residing in the United Kingdom. Study participants answered detailed questions about their cannabis use history, underwent magnetic resonance imaging (MRI), and
White House Doubles Down on Support for Marijuana Rescheduling Despite Pushback From Former Drug Czar
The White House is standing firm on President Trump’s decision to move marijuana from Schedule I to Schedule III under federal law, pushing back against criticism from former drug czar Bill Bennett. Bennett, who served as Education Secretary under President Ronald Reagan and later as the nation’s first “drug czar” under President George H.W. Bush, told Fox News Digital that while he supports most of Trump’s agenda, he opposes the move to reschedule marijuana. “I love Donald Trump,” Bennett said in comments reported by Fox News. “I
Study Suggests CBD Could Reduce the Delayed “Second Phase” of Damage Following Traumatic Brain Injury
A recent review in the journal Current Opinion in Toxicology by scientists from Gazi University suggests that cannabidiol (CBD) might help reduce the delayed “second phase” of damage that often occurs after a traumatic brain injury (TBI). The researchers note that the first wave of injury is caused by the physical impact itself, but additional harm can continue spreading through the brain over the following hours and days. This secondary phase is fueled by mechanisms like excessive glutamate activity, inflammatory responses, and metabolic disturbances —
Best-Selling Cannabis Strains of 2025: Nationwide Trends and Top Picks
Discover the best-selling cannabis strains of 2025 nationwide and by state. Explore trends, top weed varieties, and what shaped this year in the cannabis industry.
The Future of Regulated Cannabis in New York: What It Means for Local Communities
Trend Focus: Legal market consolidation + enforcement against unregulated markets As New York strengthens enforcement against unregulated sellers, licensed dispensaries are becoming pillars of trust and safety. In communities like Olean, buying from a state-licensed dispensary isn’t just about access — it’s about accountability. This article can explore:
