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Using a combination of data provided by state cannabis commissions, the strain review site Leafly, and the research firm Headset, below is a list of the most popular cannabis strains throughout the United States as of March, 2026.
Blue Dream
Blue Dream continues to hold its place as the most recognizable and widely embraced strain in the country. Although it hasn’t topped the most popular strain list in several months, its increased presence going into March, 2026 puts it back on top. It remains the most sold strain in several legal cananbis states including Alaska and California. Its staying power comes from broad appeal, strong availability and a reputation for delivering a balanced experience that keeps consumers coming back.
Runtz
Runtz remains one of the most in-demand modern strains in the U.S., with especially strong momentum in state-by-state sales data. It was the top-selling strain in February in Delaware, Michigan and Nevada. The strain’s sweet profile and strong brand recognition have helped it hold national relevance well beyond its initial rise.
Wedding Cake
Wedding Cake continues to be one of the country’s most dependable heavy-hitters. It ranked No. 3 on Leafly’s national bestselling list for 2025 and was still leading state markets in February 2026, including Rhode Island and Washington, according to the research firm Headset. It has managed to stay popular as newer dessert strains enter the market, which says a lot about its durability with consumers.
Gelato
Gelato remains a national staple, blending legacy appeal with continued market strength. Even when newer Gelato descendants grab headlines, the original still holds a strong place in the broader U.S. strain conversation.
Permanent Marker
Permanent Marker has quickly become one of the hottest strains in the country, especially in western markets. Unlike some fast-rising strains that fade just as quickly, Permanent Marker appears to be translating hype into sustained national demand.
Sour Diesel
Sour Diesel has shown impressive staying power at a time when many old-school strains have slipped. It ranked No. 4 on Leafly’s national bestseller list for 2025, and was still the top-selling strain in New Mexico in February 2026. That combination of legacy demand and current market relevance keeps it firmly in the national top tier.
Granddaddy Purple
Apple Fritter
Animal Face
Jack Herer
Honorable Mentions
Pineapple Express
OG Kush
Lemon Cherry Gelato
Super Boof
Gorilla Glue (GG4)
Biscotti
Ice Cream Cake
Kush Mints
Strawberry Cough
Jealousy
Zkittlez
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