A study published by the journal Progress in Neuro-Psychopharmacology and Biological Psychiatry found that a full-spectrum CBD extract reduced relapse-like methamphetamine seeking and meth-triggered hyperactivity in an animal model better than CBD alone. Researchers from Macquarie University and University of Sydney tested whether a multi-cannabinoid hemp extract could outperform a single-cannabinoid CBD isolate in several established rat models used to study drug-seeking and relapse. For the study, male Sprague-Dawley rats were trained to self-administer methamphetamine by lever press, then underwent extinction sessions where lever presses no longer

A new review published in Biomedicines is adding to the growing body of research suggesting that cannabidiol (CBD) could play a meaningful role in bone health. Conducted by researchers from Universiti Kebangsaan Malaysia, the scoping review examined 24 original studies exploring how CBD affects bone-related outcomes across a range of experimental models. The researchers conducted a systematic search of major scientific databases and analyzed studies regardless of design, focusing on CBD’s effects on bone formation, mineralization, strength, and underlying biological mechanisms. Of the 24 studies

A case report published in Current Neuropharmacology by researchers from the University of Catania details how a combination of cannabis oil and physiotherapy was associated with substantial improvements in a patient suffering from post-stroke dystonic tremor and post-stroke thalamic pain, two conditions that are often difficult to treat with conventional medications. Post-stroke tremor and thalamic pain are known to significantly reduce quality of life, and standard pharmacological treatments frequently provide limited relief. While cannabis has been explored for its potential role in treating movement disorders and chronic

New research published in the peer-reviewed journal Pharmaceuticals and conducted by researchers from the University of Galway found that cannabidiol (CBD) may reduce pain associated with surgical-type wounds.Using male Sprague-Dawley rats, researchers created a small incision on the dorsum (back) to model wound-related pain, a condition that remains common and often poorly managed in clinical settings. Mechanical pain sensitivity was measured over several days using standardized von Frey tests on both the wound site and the hind paws to assess primary and secondary hypersensitivity. By the eighth

Research studying the effects of cannabis on the brain has often focused on adolescents, but a new study from CU Anschutz researchers looks at population-level impacts of cannabis usage on the brain in older adults. The work is published in the Journal of Studies on Alcohol and Drugs. “More older adults are using cannabis. It’s more widely available and is being used for different reasons than in younger folks—such as for sleep and chronic pain,” said Anika Guha, Ph.D., a clinical psychologist and faculty research associate in the

Aging adults with a history of cannabis use exhibit greater cognitive performance than those with no or little history of past use, according to data published in the Journal of Studies on Alcohol and Drugs.   A team of researchers affiliated with the University of Colorado and Georgia Tech assessed cognitive performance and brain volume in a nationally representative sample of more than 500,000 adults (ages 40-70) residing in the United Kingdom. Study participants answered detailed questions about their cannabis use history, underwent magnetic resonance imaging (MRI), and

The White House is standing firm on President Trump’s decision to move marijuana from Schedule I to Schedule III under federal law, pushing back against criticism from former drug czar Bill Bennett. Bennett, who served as Education Secretary under President Ronald Reagan and later as the nation’s first “drug czar” under President George H.W. Bush, told Fox News Digital that while he supports most of Trump’s agenda, he opposes the move to reschedule marijuana. “I love Donald Trump,” Bennett said in comments reported by Fox News. “I